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I, therefore, utilized stratified activities to describe the relationship ranging from time and you will Na of the being obese updates (Figure 3)

I, therefore, utilized stratified activities to describe the relationship ranging from time and you will Na of the being obese updates (Figure 3)

Basic, the brand new hill of your relationships BP with Na consumption ranged by the opportunity intake, suggesting one Na thickness can get reflect the partnership which have BP best than just natural Na consumption do

There was a significant 3-way interaction between Na intake, energy, and obesity status for SBP (P=0.033); for DBP, the 3-way interaction was not significant, but there was a significant interaction between energy intake and obesity (P=0.005). In stratified models, the association of Na with SBP was stronger at lower energy intake (higher Na density) than at higher energy intake (lower Na density) in both nonobese (interaction of Na with energy; P<0.001) and obese (interaction of Na with energy; P=0.028); the association of Na and DBP by energy intakes was similar (interaction of Na with energy, P=0.005 nonobese; P=0.049 obese). On the control diet at 2300 mg Na intake in the nonobese, SBP was 4.7 mm Hg (95% CI, 1.0, 8.5) higher at 2100 kcal compared with 3200 kcal (Figure 3A), and DBP was 3.1 mm Hg (95% CI, 0.7, 5.5) higher (Figure 3C). In obese at 2300 mg Na intake on the control diet, there were no differences in SBP (0.6 mm Hg; 95% CI, ?3.8 to 4.9; Figure 3B) or DBP (1.8 mm Hg; 95% CI, ?1.0 to 4.5; Figure 3D) between 2100 and 3200 kcal. On the DASH diet at 2300 mg Na, there were no significant differences in SBP at 2100 versus 3200 kcal regardless of obesity status (2.5 mm Hg; 95% CI, ?1.0 to 6.0 for nonobese and ?1.3 mm Hg; 95% CI, ?6.0 to 3.4 for obese). On the DASH diet at 2300 mg Na, DBP was higher at 2100 versus 3200 kcal in the nonobese (2.1 mm Hg; 95% CI, 0.1–4.4), but not in the obese (?0.3 mm Hg (95% CI, ?3.2 to 2.6).

Figure 3. Interaction of absolute Na intake and energy intake on blood pressure at 3 energy levels stratified by obesity status, indicating 3 levels of Na density (L, I, and H), among normal and overweight (body mass index [BMI] <30 kg/m 2 , A and C) and obese (BMI?30 kg/m 2 , B and D) participants on the control diet. The vertical line is drawn at 2300 mg absolute Na intake. Error bars represent ±1 SE. Results from mixed-effects models of continuous Na and energy, adjusted for age, sex, race, smoking, cohort, diet type (DASH [Dietary Approaches to Stop Hypertension] or control), clinical center, and carryover effects stratified by obesity status. DBP indicates diastolic blood pressure; and SBP, systolic blood pressure.


So it investigation are used to decide whether or not the relationships ranging from Na and you will BP may differ which have time intake. Numerous secret conclusions emerged. 2nd, while the in the past stated, the outcome of Na prevention is attenuated in the mode regarding the Dash diet plan compared with the latest control diet plan, recommending you to regions of diet in addition to influence new BP reaction to alterations in Na intake. 5,several,13 And additionally attenuating the BP reaction to Na, the newest Dash eating plan including reduced BP, in line with research one to areas of diet, together with a greater consumption out-of potassium, separately down BP. fourteen Third, the newest association of Na which have opportunity consumption on the BP proceeded when the analyses was in fact stratified by the race, with the exception of DBP certainly whites. 4th, which have stratification by obesity updates, large differences in BP from the energy intake were observed those types of who had been nonobese weighed against overweight.

While the Dashboard–Na study controlled Na occurrence, rather than sheer talkwithstranger hesap silme Na intake, the first consequence of it demo had been translated when it comes to Na consumption rather than Na occurrence. The possible lack of revealing abilities of the Na occurrence will get reflect the latest lack of research for the time intake a number of knowledge. Investigations of your own relationships regarding Na occurrence that have death inside the observational research has offered blended performance. The analysis off Na occurrence that have mortality regarding NHANES II follow-up analysis (Federal Health and Nutrition Examination Survey) and you may from NHANES III advised an inverse organization regarding Na and you can cardiovascular disease death, whether or not considering Na with regards to time consumption. fifteen,sixteen During these knowledge, although not, Na and effort intake had been estimated using one twenty-four-hours keep in mind, that isn’t enough to estimate your usual dietary consumption on account of high time-to-day type in Na intake and energy intake and their ratio. Then, opportunity intake try implausibly reduced in both degree. You’ll be able to the seen relationship anywhere between Na consumption and you can heart problems mortality tends to be told me by the less than-reporting bias, that’s, in the event the over weight some body statement straight down Na thickness and are more likely in order to perish out-of cardiovascular disease, the fresh seen relationships will get mirror the latest effect off being obese in lieu of eating plan. The most up-to-date proof from a possible cohort investigation (n=716, 19-12 months pursue-up) aligns on the results of the modern investigation, with reported incidence off cardiovascular occurrences twice as highest one particular regarding the high in place of lower quartile out-of Na density (22% in the place of eleven%, respectively; P=0.005) considering eight-big date restaurants ideas compiled at the standard. 17

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